Specialty Imaging: HRCT of the Lung - E-Book, 3rd Edition

SECTION 1: FUNDAMENTALS OF HRCT
Overview of HRCT
Approach to HRCT Interpretation
ANATOMY
Interstitial Compartments
Secondary Pulmonary Lobule
Gravitational Changes (Dependent Atelectasis)
Age-Related Changes
Normal Inspiration and Expiration
TERMINOLOGY AND SIGNS
3-Density Sign (Formerly Head Cheese Sign)
Airspace Nodules
Anterior Upper Lobe Sign
Crazy Paving
Cystic Lung Disease
Exuberant Honeycombing
Finger-in-Glove Sign
Flame-Shaped Nodules
Four Corners Sign
Ground Glass
Halo Sign
Honeycombing (Peribronchovascular)
Honeycombing (Subpleural)
Honeycombing (Unilateral)
Micronodules
Mosaic Attenuation and Air-Trapping
Reversed Halo Sign
Signet-Ring Sign
Straight-Edge Sign
Tree-in-Bud Opacities
Thick-Walled Cystic Lesions (Stalactite and Stalagmite Sign)
DISTRIBUTION
Peribronchovascular
Centrilobular
Perilymphatic
Random
Peripheral

SECTION 2: PATHOLOGIC PATTERNS OF INJURY
Approach to Pathologic Patterns of Injury
Diffuse Alveolar Damage
Diffuse Alveolar Hemorrhage With Capillaritis
Organizing Pneumonia
Constrictive Bronchiolitis

SECTION 3: LARGE AIRWAYS DISEASE
Approach to Large Airways Disease
Bronchiectasis
Allergic Bronchopulmonary Aspergillosis
Williams-Campbell Syndrome
Mounier-Kuhn Syndrome
Bronchocentric Granulomatosis

SECTION 4: SMALL AIRWAYS DISEASE
Approach to Small Airways Disease
Infectious Bronchiolitis
Asthma
Diffuse Aspiration Bronchiolitis
Respiratory Bronchiolitis
Follicular Bronchiolitis
Hypersensitivity Pneumonitis
Diffuse Panbronchiolitis
Idiopathic Constrictive Bronchiolitis
Swyer-James-MacLeod Syndrome
Bronchiolitis Obliterans Syndrome
Diffuse Idiopathic Pulmonary Neuroendocrine Cell
Hyperplasia (DIPNECH)

SECTION 5: INFECTION
Approach to Infection
Bacterial Pneumonia
Mycoplasma Pneumonia
Staphylococcus aureus Pneumonia
Viral Pneumonia
Influenza
COVID-19
Respiratory Syncytial Virus
Cytomegalovirus
Tuberculosis
Nontuberculous Mycobacterial Infection
Endemic Fungal Infection
Cryptococcosis
Aspergillosis
Pneumocystis Pneumonia
Candidiasis

SECTION 6: PNEUMOCONIOSIS
Approach to Pneumoconiosis
Silicosis and Coal Worker's Pneumoconiosis
Asbestosis
Berylliosis
Talcosis
Hard Metal Lung Disease

SECTION 7: NEOPLASMS
Approach to Neoplasms
Invasive Mucinous Adenocarcinoma (Diffuse)
Diffuse and Multifocal Lung Cancer
Lymphangitic Carcinomatosis
Hematogenous Metastases
Endovascular Metastases and Tumor Emboli
Kaposi Sarcoma
Lymphangioleiomyomatosis
Reactive Lymphoproliferative Disorders
Neoplastic Lymphoproliferative Disorders
Pulmonary Langerhans Cell Histiocytosis
Erdheim-Chester Disease
Rosai-Dorfman Disease
Diffuse Pulmonary Meningotheliomatosis (DPM)

SECTION 8: INTERSTITIAL PNEUMONIAS
Approach to Interstitial Pneumonias
Interstitial Lung Abnormality (ILA)
Idiopathic Pulmonary Fibrosis
Progressive Pulmonary Fibrosis (PPF)
Idiopathic Nonspecific Interstitial Pneumonia
Cryptogenic Organizing Pneumonia
Acute Exacerbation of Interstitial Lung Disease
Acute Interstitial Pneumonia
Idiopathic Lymphoid Interstitial Pneumonia
Pleuroparenchymal Fibroelastosis
Airway-Centered Interstitial Fibrosis
Interstitial Pneumonia With Autoimmune Features (IPAF)
Approach to Smoking-Related Interstitial Lung Diseases
Respiratory Bronchiolitis-Interstitial Lung Disease
Desquamative Interstitial Pneumonia
Syndrome of Combined Pulmonary Fibrosis and Emphysema
Smoking-Related Interstitial Fibrosis (SRIF)
Airspace Enlargement With Fibrosis (AEF)

SECTION 9: AUTOIMMUNE DISEASES
Approach to Connective Tissue Disease-Associated Interstitial Lung Disease
Rheumatoid Arthritis
Progressive Systemic Sclerosis
Idiopathic Inflammatory Myopathies
Sjögren Syndrome
Mixed Connective Tissue Disease
Systemic Lupus Erythematosus
Granulomatosis With Polyangiitis (GPA)
Eosinophilic Granulomatosis With Polyangiitis
Microscopic Polyangiitis
Ankylosing Spondylitis
Inflammatory Bowel Disease-Associated Lung Disease

SECTION 10: VASCULAR DISEASE
Approach to Vascular Disease
Pulmonary Edema
Hepatopulmonary Syndrome
Pulmonary Hypertension
Pulmonary Venoocclusive Disease/Pulmonary
Capillary Hemangiomatosis
Excipient Lung Disease (Talc/Cellulose Granulomatosis)
Chronic Thromboembolic Pulmonary Hypertension

SECTION 11: INHALATIONAL, INFLAMMATORY, METABOLIC, AND POST TREATMENT
Approach to Inhalational, Inflammatory, Metabolic, and Post Treatment
ASPIRATION/INHALATION
Spectrum of Aspiration-Related Disorders
Lipoid Pneumonia
Inhalational Lung Injury
E-Cigarette or Vaping Product Use-Associated Lung Injury (EVALI)
Recurrent Gastric Acid Aspiration and Dendriform
Pulmonary Ossification
INFLAMMATORY
Sarcoidosis
Acute Eosinophilic Pneumonia
Chronic Eosinophilic Pneumonia
Other Eosinophilic Disorders
METABOLIC OR DEGENERATIVE
Amyloidosis
Light Chain Deposition Disease
Pulmonary Alveolar Proteinosis
Metastatic Pulmonary Calcification
Diffuse Pulmonary Ossification
Emphysema
Idiopathic Pulmonary Hemosiderosis
POST TREATMENT
Radiation-Induced Lung Disease
Drug-Induced Lung Disease
Immune Checkpoint Inhibitor-Related Pneumonitis

SECTION 12: CONGENITAL
Approach to Congenital
Familial Idiopathic Pulmonary Fibrosis
Birt-Hogg-Dubé Syndrome
Hermansky-Pudlak Syndrome
Tuberous Sclerosis Complex
Neurofibromatosis
Alveolar Microlithiasis
α-1 Antitrypsin Deficiency
Primary Ciliary Dyskinesia
Chronic Granulomatous Disease
Common Variable Immunodeficiency
Primary Immunodeficiency Disorders
Cystic Fibrosis
Childhood Interstitial Lung Disease (chILD)
Diffuse Pulmonary Lymphangiomatosis
Proximal Interruption of Pulmonary Artery

"This book, written by established thoracic radiologists in the US, contains 577 pages of beautifully illustrated radiology, histopathology and anatomical line images supplemented by easy-to-understand text covering the important pathological and imaging features of a host of different conditions falling under the ‘pathological sieve’ and even some rare conditions. It includes PETCT images, where relevant. The chapter on fundamentals of HRCT is outstanding and the accompanying illustrations are first rate. The reader needs to get a full grasp of anatomical considerations before understanding HRCT patterns and this section more than achieves that aim. The text and illustrations of the secondary pulmonary lobule are superb." Review by Dr Janine Lee, consultant chest radiologist, Aintree University Hospital and Dr John Curtis, RAD Magazine, March 2026

"The third edition of Specialty Imaging: HRCT of the Lung was edited by Santiago Martínez-Jiménez, Professor of Radiology at the University of Missouri-Kansas City School of Medicine, Kansas City, Missouri, USA; Melissa L. Rosado-de-Christenson, Professor of Medical Imaging, University of Arizona College of Medicine – Tucson, Tucson, Arizona, USA; and Sherief H. Garrana, Clinical Assistant Professor of Radiology, NYU Langone Health, New York, NY, USA, in collaboration with leading experts in the field. Coming seven years after the previous edition, it represents a necessary and authoritative update to one of the most established reference texts in thoracic imaging. The book, essential for the correct interpretation of the CT signs of lung’s diseases, is part of the excellent and authoritative Specialty Imaging series, continuing its tradition of comprehensiveness, clinical and radiological relevance." Review by Luigi Mansi, European Journal of Nuclear Medicine and Molecular Imaging, 2026

Review of the previous edition:
"The book covers the whole spectrum of diseases of the chest imaged HRCT. The coverage of interstitial lung diseases is particularly excellent. Plentiful illustrations accompany the text, as is necessary for a subject of this nature. It is notable that the book pays good attention to differential diagnoses for each condition, as well as differentiating factors to weigh each of them, which is of direct value in day-to-day clinical practice.... This new edition is a valuable update of its predecessor, and an excellent addition to the field. This is a great resource for both reference and complete review." -Reviewed by Nikhil Madhripan, MD (Baystate Medical Center) Doody's Score: 92, 4 Stars!