Advances in Molecular Pathology Volume 2.1 Table of Contents
Preface
Molecular Pathology: Unraveling the Underlying Complexities of Human Disease
By Gregory J. Tsongalis
Genetics
The Evolution of Constitutional Sequence Variant Interpretation
By Jessica Mester and Tina Pesaran
The Future of Clinical Diagnosis: Moving Functional Genomics Approaches to the Bedside
By Rini Pauly and Charles E. Schwartz
Genomic Data in the Electronic Health Record
By Nephi A. Walton, Darren K. Johnson, Thomas N. Person, and Srikar Chamala
Hematopathology
Molecular Genetics in Myelodysplasia Outcomes Prognostication
By Lucas H. Rifkin and Eric Y. Loo
Assessing Measurable Residual Disease in Acute Myeloid Leukemia
By Daniel L. Duncan, Joshua F. Zeidner, and Nathan D. Montgomery
Philadelphia-Like Lymphoblastic Leukemia: Approach to Testing in Clinical Laboratories for Diagnosis, Prognosis, and Therapeutic Risk Assessment
By Michelle Afkhami
Myeloid Gene Panel Testing with Correlation to Updated Clinical Practice Guidelines
By Laura N. Toth and Daniel Babu
Infectious Disease
Impact of Molecular Diagnostics on Antimicrobial Stewardship
By Sheila M. Johnson, Mackenzie E. Collins, and Melissa B. Miller
Application of Next-Generation Sequencing in Public Health Epidemiology and Outbreak Investigation
By Anthony Tran and Marie-Claire Rowlinson
Next-Generation Sequencing Approaches to Predicting Antimicrobial Susceptibility Testing Results
By Rebecca Yee and Patricia J. Simner
Pharmacogenomics
Artificial Intelligence and Pharmacogenomics: A Timely Synergy for Individualizing Medicine
By Ravishankar K. Iyer, Arjun P. Athreya, Liewei Wang, and Richard M. Weinshilboum
The Evolution of DNA Sequencing in Pharmacogenomics
By Steven E. Scherer
Consumer-initiated Genetic Testing and Pharmacogenomics
By Ann M. Moyer and Linnea M. Baudhuin
Informatics
Machine Learning in Biology and Medicine
By Javad Noorbakhsh, Harshpreet Chandok, R. Krishna Murthy Karuturi, and Joshy George
Solid Tumors
Clinical Use of Cell-Free DNA in Tumor Diagnostics
By Tejus A. Bale and Maria E. Arcila
Practical Concepts, Current Challenges, and Technological Advances in Clinical Next- Generation Sequencing Assays for Solid Tumors
By Mir B. Alikhan, Mustafa Al-Kawaaz, Karen Kaul, and Linda Sabatini
Evidence Builds for Tumor Mutation Burden as an Immunotherapy Biomarker
By Andrea Ferreira-Gonzalez
Identity/HLA
Human Leukocyte Antigen Typing Using High- Throughput DNA and RNA Sequencing and Application for Cell Line Identification
By Sebastian Boegel and John C. Castle
Expanding the Connectivity Map Concept as the Functional Look-Up Table for Systems Biology
By Bernard Kok Bang Lee, Sok Ching Cheong, and Aik Choon Tan
