Within this one volume both basic science and clinical immunology are demystified for the medical and other health sciences student. The basic immunological processes are described first, with a level of detail restricted to what is appropriate for medical (and similar) curricula. In the second part of the book, immunological mechanisms behind major diseases of the various body systems are explained. Throughout the text clinical details are highlighted and more in-depth material is differentiated from the main text.
New to this edition
Now full-colour throughout
Specialised material removed and replaced with clearer introductory explanations
Clearer illustrations, thanks to rewritten captions
Key Features
- Covers both basic science and clinical immunology in one volume
- Specifically aimed at medical students and appropriate for integrated system-based curricula
- Main text supported by 'in depth', key point and clinical boxes
Author Information
By Mark Peakman, MBBS, PhD, FRCPath, Professor of Immunology, King's College London; Honorary Consultant Immunologist, King's College Hospital, London, UK; Diego Vergani, MD, PhD, FRCPath, FRCP, Professor of Liver Immunopathology, King's College London and Honorary Consultant Immunologist, King's College Hospital, London, UK
Anatomy and cells of the immune system. Innate immunity I: physical and humoral protection. Innate immunology II: cellular mechanisms. Acquired immunity: antigen receptors. The human leukocyte antigens. Cellular immune responses I: dendritic cells, macrophages and B lymphocytes. Cellular immune responses II: T lymphocytes, antigen presentation and natural killer cells. The immune response to microbes: an overview. Tolerance and mechanisms of autoimmunity. Hypersensitivity reactions and clinical allergy. Transplantation. Rheumatic diseases. Endocrine autoimmune disease. Liver diseases. Gastrointestinal diseases. Immune-mediated nephritis and vasculitis. Immune-mediated skin disease. Immune-mediated diseases of the nervous system and eye. Immunodificiency. Human immunodeficiency virus and AIDS. Immunological manifestations of haematological disease. Immune-based therapies. Immunisation.
"This book was a joy to read and both authors deserve credit for putting across difficult concepts of immunology in a very simple and effective way...This book is highly recommended to medical students, trainee clinical scientists and speciality medical trainees to master the concepts of basic immunology." The Bulletin, October 2009