Radiosurgery of the Skull Base: A Case-Based Approach explores non-invasive treatment of skull base pathologies using radiosurgery—all with a practical, case-based approach. This succinct, easy-to-navigate clinical reference covers stereotactic radiosurgery of skull base lesions, allowing you to quickly look up a specific pathology and tailor your radiosurgical strategy accordingly for the best treatment plan.
Key Features
- Covers the basics of radiosurgery, including fundamentals of radiobiology, dose tolerances, and particle therapy, as well as how and when to utilize radiosurgery in patients with skull base tumors.
- Provides a pragmatic and structured approach to more than 50 pathologies along various regions of the skull base.
- Includes tumor treatment plans for various pathologies, including vestibular and facial schwannomas, pituitary adenomas, meningiomas, chordomas, trigeminal neuralgia, metastases, and more.
- Presents cases based on real patient scenarios, with thorough descriptions of planning, dosages, outcomes, and follow-up images.
- Discusses the dose tolerance of surrounding structures, which influences the overall treatment plan.
- Any additional digital ancillary content may publish up to 6 weeks following the publication date.
Author Information
Edited by Siviero Agazzi, MD, MBA, Chief of Cranial Surgery and Chief of Radiosurgery, University of South Florida, Tampa, Florida; Lawrence Berk and Mohammad Hassan A. Noureldine
SECTION 1
Skull Base Radiosurgery: The Basics
1 Stereotactic Radiosurgery Machines
2 Fundamentals of Radiobiology for Radiosurgery
3 Stereotactic Radiosurgery/Radiotherapy with Particle Therapy
4 Dose Tolerances of Normal Tissues in Skull Base Radiosurgery
SECTION 2
Olfactory Groove/Planum Sphenoidale/Paranasal Region
5 Esthesioneuroblastoma – Delayed Postoperative Radiosurgery for Recurrence at Short-Term
6 Esthesioneuroblastoma – Delayed Postoperative Radiosurgery for Recurrence at Long-Term
7 Olfactory Groove Meningioma – Upfront Radiosurgery
8 Planum Sphenoidale Meningioma – Upfront Radiosurgery
9 Planum Sphenoidale/Orbital Roof Meningioma – Delayed Postoperative Radiosurgery for Recurrence
10 Paranasal Sinus Melanoma – Definitive Stereotactic Body Radiation Therapy
SECTION 3
Sellar/Suprasellar/Parasellar Region – Pituitary Adenoma
11 Null Cell – Delayed Postoperative Radiosurgery for Growing Intracavernous Residual
12 Null Cell – Delayed Postoperative Radiosurgery for Growing Perioptic Residual
13 ACTH Secreting – Delayed Postoperative Radiosurgery of Gland for Recurrent Pathology-Negative Cushing Disease
14 Growth Hormone Secreting – Immediate Postoperative Radiosurgery for Residual
15 Prolactinoma – Immediate Postoperative Radiosurgery for Residual
SECTION 4
Sellar/Suprasellar Region – Other Than Pituitary Adenoma
16 Craniopharyngioma – Delayed Postoperative Radiosurgery for Recurrence
17 Tuberculum Sella Meningioma – Upfront Radiosurgery
18 Suprasellar Meningioma – Immediate Postoperative Radiosurgery for Residual
19 Suprasellar Non-Small Cell Lung Carcinoma Metastasis – Upfront Radiosurgery
SECTION 5
Parasellar Space/Cavernous Sinus Region
20 Trigeminal Schwannoma – Upfront Radiosurgery
21 Trigeminal Schwannoma – Upfront, StagedVolume Radiosurgery
22 Cavernous Sinus Meningioma – Upfront Radiosurgery
23 Cavernous Sinus Meningioma – Immediate Postoperative Radiosurgery for Perioptic Residual
24 Cavernous Sinus Meningioma – Immediate Postoperative Radiosurgery for Residual Tumor After Repeat Resection
SECTION 6
Clivus/Petroclival Junction
25 Chondrosarcoma – Definitive Radiosurgery After Subtotal Resections
26 Chordoma – Immediate Postoperative/PostProton Therapy Radiosurgery for Residual Disease
27 Cavernous Sinus/Petroclival Meningioma – Immediate Postoperative Radiosurgery for Residual/Postoperative Radiosurgery for Recurrence
28 Chondrosarcoma/Trigeminal Neuralgia – Upfront, Multisession Radiosurgery/Postoperative Radiosurgery for Trigeminal Neuralgia
SECTION 7
Cerebellopontine Angle Region – Other Than Vestibular Schwannoma
29 Petrous Apex Meningioma – Upfront Radiosurgery
30 Sphenopetroclival Meningioma – Delayed Postoperative Radiosurgery for Growing Residual
31 Petrous Ridge/Sigmoid Sinus Meningioma – Upfront Radiosurgery
32 Petrosal Surface/Sigmoid Sinus Meningioma – Delayed Postoperative Multisession Radiosurgery for Growing Residual
33 Endolymphatic Sac Tumor – Immediate Postoperative Radiosurgery of Surgical Bed
34 Cisternal Trigeminal Schwannoma – Upfront Radiosurgery
35 Trochlear Schwannoma – Upfront Radiosurgery
SECTION 8
Internal Auditory Canal/Cerebellopontine Angle Region – Vestibular Schwannoma and Facial Schwannoma
36 Medium Vestibular Schwannoma without Hearing Deficit – Upfront Radiosurgery
37 Medium Vestibular Schwannoma with Hearing Deficit – Upfront Radiosurgery
38 Large Vestibular Schwannoma – Immediate Postoperative Radiosurgery for Residual
39 Large Vestibular Schwannoma – Delayed Postoperative Radiosurgery for Growing Residual
40 Small Vestibular Schwannoma with Hearing Deficit – Upfront Radiosurgery
41 Small Facial Schwannoma with Hearing Deficit – Upfront Radiosurgery
SECTION 9
Trigeminal Neuralgia
42 Trigeminal Neuralgia due to Microvascular Conflict – Upfront Radiosurgery
43 Idiopathic Trigeminal Neuralgia – Upfront Radiosurgery
44 Trigeminal Neuralgia due to Trigeminal Schwannoma – Upfront Radiosurgery
45 Trigeminal Neuralgia due to Petroclival Meningioma – Upfront Radiosurgery
SECTION 10
Jugular Foramen Region
46 Capillary Hemangioma – Postoperative Radiosurgery for Residual Tumor
47 Jugular Foramen/Sigmoid Sinus Meningioma – Postoperative Radiosurgery for Residual Tumor
48 Jugular Foramen Meningioma – Upfront Radiosurgery
49 Jugular Paraganglioma – Postoperative Radiosurgery for Residual Tumor
50 Jugular Paraganglioma – Upfront Radiosurgery
51 Vagal Schwannoma – Postoperative Radiosurgery for Residual Tumor
52 Jugular Foramen Schwannoma – Upfront Radiosurgery
53 Jugular/Clival Paraganglioma – Delayed Postembolization, Multisession Radiosurgery for Growing Residual
SECTION 11
Foramen Magnum/Clivus Region
54 Foramen Magnum Meningioma – Upfront Radiosurgery
55 Foramen Magnum/Petroclival Meningioma – Immediate Postoperative Radiosurgery for Residual
56 Occipital Condyle/Clivus/C1 Vertebra Metastasis – Upfront Stereotactic Body Radiation Therapy
SECTION 12
Major Sinuses
57 Superior Sagittal/Transverse Sinuses Meningioma – Immediate Postoperative, Staged-volume Radiosurgery for Residual/Delayed Postoperative Radiosurgery for Growing Residual
58 Superior Sagittal Sinus Meningioma – Delayed Postoperative, Multisession Radiosurgery for Growing Residual
59 Superior Sagittal Sinus Meningioma – Immediate Postoperative Radiosurgery for Residual
60 Torcular/Tentorial Meningioma – Upfront Radiosurgery
61 Transverse Sinus Dural Arteriovenous Fistula – Upfront, Preembolization Radiosurgery
62 Tentorial Dural Arteriovenous Fistula – Upfront Radiosurgery
