Make sure you are thoroughly prepared to work in a clinical laboratory. Rodak’s Hematology: Clinical Principles and Applications, 7th Edition uses hundreds of full-color photomicrographs to help you understand the essentials of hematology and hemostasis. This new edition details the parts and functions of the cell; shows how to accurately identify cells; covers normal hematopoiesis through diseases of erythroid, myeloid, lymphoid, and megakaryocytic origins; and simplifies hemostasis and thrombosis concepts and disorders. Easy to follow and understand, this book also covers key topics, including working in the hematology and hemostasis laboratory; complementary testing areas such as flow cytometry, cytogenetics, and molecular diagnostics; and laboratory testing of blood cells and body fluid cells.
New to this edition
New to this edition
- NEW! Chapter on Patient Safety in Hematology and Hemostasis.
- NEW! Section on hematology and hemostasis in transgender populations.
- UPDATED! White blood cell chapters are current with the 2022 World Health Organization (WHO) Classification of Haematolymphoid Tumours.
- NEW! Changes in laboratory results associated with COVID-19 and other viral infections.
- NEW! Content and figures on plasma transport, cell communication, and signal transduction.
- NEW! Coverage of CRISPR technology for treatment of hemoglobinopathies and thalassemia.
- UPDATED! Major revision of the Automated Blood Cell Analysis chapter.
Key Features
Over 700 full-color illustrations and photomicrographs make it easier for students to visualize hematology concepts and show what they’ll encounter in the lab, with images appearing near their mentions in the text to minimize flipping pages back and forth. Content throughout text reflects latest information on hematology. Instructions for lab procedures include sources of possible errors along with comments. Hematology instruments are described, compared, and contrasted. Case studies in each chapter provide opportunities to apply hematology concepts to real-life scenarios. Hematology/hemostasis reference ranges are listed on the inside front and back covers for quick reference. A bulleted summary makes it easy for students to review the important points in every chapter. Learning objectives begin each chapter and indicate what students should achieve, with review questions appearing at the end.
Author Information
Edited by Elaine M. Keohane, PhD, MLS(ASCP)SHCM, Professor Emeritus, Clinical Laboratory and Medical Imaging Sciences, School of Health Professions, Rutgers, The State University of New Jersey, Newark, New Jersey; Michelle Montgomery Preston, PhD, MLS(ASCP)CM, Associate Professor, Pathology, Anatomy, and Laboratory Medicine, Vice Chair, Biomedical Laboratory Diagnostics Program Director, Medical Laboratory Science, School of Medicine, West Virginia University, Morgantown, West Virginia; Kamran M. Mirza, MD, PhD, FCAP, FASCP, MLS(ASCP)CM, Clinical Professor of Pathology, Director, Division of Education Programs, Pathology, Michigan Medicine, Ann Arbor, Michigan and Jeanine M. Walenga, PhD, MLS(ASCP)HCM, Professor, Thoracic-Cardiovascular Surgery, Pathology, and Physiology, Co-Director, Hemostasis and Thrombosis Research Unit, Stritch School of Medicine, Loyola University Chicago, Laboratory Director, Clinical Coagulation, Laboratory Director, Urinalysis and Medical Microscopy, Associate Director, Point of Care & Referred Testing, Pathology and Laboratory Medicine, Loyola University Health System, Maywood, Illinois
Part I. Introduction to Hematology
1. An Overview of Clinical Laboratory Hematology
2. Patient Safety in Hematology and Hemostasis
3. Quality Assurance in Hematology and Hemostasis Testing
Part II. Blood Cell Production, Structure, and Function
4. Cell Structure and Function
5. Hematopoiesis
6. Erythrocyte Production and Destruction
7. Erythrocyte Metabolism and Membrane Structure and Function
8. Hemoglobin Metabolism
9. Iron Kinetics and Laboratory Assessment
10. Leukocyte Development, Kinetics, and Functions
11. Platelet Production, Structure, and Function
Part III. Laboratory Evaluation of Blood Cells
12. Manual, Semiautomated, and Point-of-Care Testing in Hematology
13. Automated Blood Cell Analysis
14. Examination of the Peripheral Blood Film and Correlation With the Complete Blood Count
15. Bone Marrow Examination
Part IV. Erythrocyte Disorders
16. Anemias: Red Blood Cell Morphology and Approach to Diagnosis
17. Disorders of Iron Kinetics and Heme Metabolism
18. Anemias Caused by Defects of DNA Metabolism
19. Bone Marrow Failure
20. Introduction to Increased Destruction of Erythrocytes
21. Intrinsic Defects Leading to Increased Erythrocyte Destruction
22. Extrinsic Defects Leading to Increased Erythrocyte Destruction - Nonimmune Causes
23. Extrinsic Defects Leading to Increased Erythrocyte Destruction - Immune Causes
24. Hemoglobinopathies (Structural Defects in Hemoglobin)
25. Thalassemias
Part V. Leukocyte Disorders
26. Nonmalignant Leukocyte Disorders
27. Introduction to Hematologic Neoplasms
28. Flow Cytometric Analysis in Hematologic Disorders
29. Molecular Diagnostics in Hematopathology
30. Cytogenetics
31. Acute Leukemias
32. Myeloproliferative Neoplasms
33. Myelodysplastic Neoplasms
34. Mature Lymphoid Neoplasms
Part VI. Hemostasis and Thrombosis
35. Normal Hemostasis
36. Hemorrhagic Disorders and Laboratory Assessment
37. Qualitative Disorders of Platelets and Vasculature
38. Quantitative Disorders of Platelets: Thrombocytopenia and Thrombocytosis
39. Thrombotic Disorders and Laboratory Assessment
40. Antithrombotic Therapies and Laboratory Assessment
41. Laboratory Evaluation of Hemostasis
42. Hemostasis and Coagulation Instrumentation
Part VII. Hematology and Hemostasis in Selected Populations
43. Hematology and Hemostasis in the Pediatric, Pregnant, Geriatric, and Transgender Populations
Appendix A. Abbreviations
Appendix B. List of Formulas
Appendix C. Answers
Appendix D. Glossary
Index
